Recent Posts

antidepressants for insomnia: the highest evidence thus far.

http://cochranelibrary-wiley.com/doi/10.1002/14651858.CD010753.pub2/epdf/abstract basically trazodone and doxepin are reasonable alternatives to z drugs

Chief complaint: Homicidal. Assessing violence risk | MDedge Psychiatry

https://www.mdedge.com/psychiatry/article/164162/chief-complaint-homicidal-assessing-violence-risk?oc_slh=a195008f33c4dd0dfa3c16ad9377076b1fbb3e1fab07e5a2e358c01ae920b082&utm_source=News_CPN_eNL_052518_F&utm_medium=email&utm_content=Is your patient likely to become violent?

Keep saying yes to fish twice a week for heart health — ScienceDaily

https://www.sciencedaily.com/releases/2018/05/180517081837.htm The advisory was written by a panel of nutrition experts, who also reviewed studies about mercury in fish. Mercury is found in most seafood but is prevalent in large fish such as shark, swordfish, tilefish, king mackerel, bigeye tuna, marlin and orange roughy. The writing group concluded that while mercury contamination may be associated […]
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Smarter brains run on sparsely connected neurons — ScienceDaily

https://www.sciencedaily.com/releases/2018/05/180517102236.htm “Intelligent brains possess lean, yet efficient neuronal connections,” concludes Erhan Genç. “Thus, they boast high mental performance at low neuronal activity.”

Brain abnormality indicates general risk for mental illness: A new study identifies functional connectivity impairments associated with transdiagnostic risk for common forms of mental illness — ScienceDaily

https://www.sciencedaily.com/releases/2018/05/180517102401.htm Authors conclude: “These patterns suggest that broad risk for mental illness may reflect subtle problems in how a person is able to integrate their thoughts, plans, and actions with their fundamental experience of the world, which in humans is principally represented by visual information,” said Mr. Elliott.

POEM: Nonopioids equivalent to opioids for severe chronic back, hip, or knee pain with fewer adverse outcomes

Begin forwarded message: From: “Joule – a CMA Company” <cma.ca> Subject: POEM: Nonopioids equivalent to opioids for severe chronic back, hip, or knee pain with fewer adverse outcomes Date: May 15, 2018 at 4:00:03 AM PDT To: “Joris Anton Josef Wiggers” <joriswiggers> Reply-To: cma.ca View the Web version POEMs Research Summaries Your daily update for […]
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Methamphetamine use and future risk for Parkinson’s disease: Evidence and clinical implications – Drug & Alcohol Dependence

https://www.drugandalcoholdependence.com/article/S0376-8716(18)30197-2/fulltext?dgcid=raven_jbs_etoc_email basically, its a real problem: Watch for PD emergence in former meth addiction.

J Clin Psychiatry/Ketamine for Depression, 1: Clinical Summary of Issues Related to Efficacy, Adverse Effects, and Mechanism of Action

http://www.psychiatrist.com/JCP/article/Pages/2017/v78n04/v78n0408.aspx Great ketamine summary

Intranasal Ketamine Succeeds for Resistant Depression

https://www.medscape.com/viewarticle/896510?nlid=122292_329&src=WNL_mdplsnews_180511_mscpedit_psyc&uac=27343DV&spon=12&impID=1630260&faf=1#vp_3 Timeline for S-ketamine intranasal spray, (Janssen), could file for product release by end of the year. Great hype. Low side effects. Good Phase 3 trial data released this month. We are hopeful to use it within 1 year? Game changer? Biggest psychopharma intro in 50 years? Lots of hype…

Long-term effects of pre-birth exposure to anti-depressants 12 years later — ScienceDaily