Category Archives: Mood Disorders

ECT for depression can be very successful and can be maintained.

Older patients (>55) with a psychotic depression and complete remission within the first four electroconvulsive therapy sessions are the ones with the best chance of remaining relapse free for at least 6 months (10% relapse rate vs. 63% others), presented by Pascal Sienaert, MD, PhD, reported at the annual congress of the European College of […]
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Medication enhanced psychotherapy

Propranolol May Help PTSD Patients Receiving Exposure Therapy While exposure therapy is recognized as one of the best strategies for treating patients with posttraumatic stress disorder (PTSD), many continue to experience significant problems. A study published in AJP in Advancesuggests that patients with PTSD who take propranolol (a noradrenergic beta-receptor blocker) prior to recalling their […]
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Case against use of antidepressants in chronic medical illnesses

Effect of sertraline on depressive symptoms in patients with chronic kidney disease without dialysis dependence: The CAST randomized clinical trial JAMA — | November 09, 2017 Hedayati SS, et al. – The researchers investigated the effect of sertraline on depressive symptoms in patients with chronic kidney disease (CKD) and major depressive disorder (MDD). Compared with […]
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Botox for Depression

Botulinum toxin as a treatment for depression in a real-world setting Journal of Psychiatric Practice — | January 12, 2018 Chugh S, et al. – The researchers evaluated the efficacy of botulinum toxin (BTX) as a treatment for depression in a real-world setting. In previous trials, it was found to be effective among women. This […]
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This easier, newer psychotherapy has growing evidence of efficacy in PTSD

A Brief Exposure-Based Treatment vs Cognitive Processing Therapy for Posttraumatic Stress DisorderA Randomized Noninferiority Clinical Trial Denise M. Sloan, PhD1,2; Brian P. Marx, PhD1,2; Daniel J. Lee, PhD1; et alPatricia A. Resick, PhD3 Author Affiliations Article Information JAMA Psychiatry. Published online January 17, 2018. doi:10.1001/jamapsychiatry.2017.4249 Key Points Question Is a brief, exposure-based treatment noninferior to […]
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Transdermal Estradiol and Micronized Progesterone for the Prevention of Depression in the Menopause Transition

This is very interesting for middle-aged women contemplating the risks and benefits of HRT. Perhaps a family history or past history of depression might tip the balance in favor of HRT? https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2668205?utm_source=undefined&utm_campaign=content-shareicons&utm_content=article_engagement&utm_medium=social&utm_term=011618#.Wl7brXb55tg.email — This message was sent by joriswiggers@gmail.com via http://addthis.com. Please note that AddThis does not verify email addresses. To stop receiving any emails […]
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Slideshow: Tips for Living Well With Depression

Very nice summary a rticle for those interested in Natural treatments of depression! Enjoy the slide show. https://www.medicinenet.com/depression_tips_pictures_slideshow/article.htm?ecd=mnl_spc_010518 Depression Symptoms: Exercise, Diet & Stress Reduction Reviewed by Joseph Goldberg, MD on Friday, October 09, 2015 Depression Tips: Exercise, Diet, Stress Reduction, and More in Pictures Sources: This tool does not provide medical advice. See additional […]
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Psycho-Pharm Medications with depression as a potential side effect

This is a latest updated article I received from my peers on a psychiatric List-Serv. The review of several medications that CAUSE depression is interesting and important to know.  Steroids can cause depression and mania and psychosis.   Dialogues Clin Neurosci. 2011;13(1):109-25. Depressogenic effects of medications: a review. Celano CM1, Freudenreich O, Fernandez-Robles C, Stern […]
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Mentalization-Based Treatment: A Common-Sense Approach to Borderline Personality Disorder | Psychiatric Times

I wanted to have this readily available: Peter Fonagy, a respected psychoanalyst in the UK has worked very hard in the recent ten years to substantiate the efficacy of psychodynamic psychotherapy for borderline personality disorder. This is his effort. Well worth reading it, as it applies broadly I think to other areas of psychological experience. […]
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S-ketamine intranasal treatment! A new approach to depression…

https://clinicaltrials.gov/show/NCT01998958 Trial data for successfully completed trial of S-ketamine intranasal therapy. Small study, needs replication and safety data. S-ketamine is purported to be safer than mixed enantiomer ketamine (special K).