Author Archives: Dr. Joris Wiggers

Incidence, prevalence and clinical correlates of antidepressant-emergent mania in bipolar depression: a systematic review and meta-analysis. – PubMed – NCBI

Antidepressants in bipolar depression: yes, no, maybe? | Evidence-Based Mental Health

Depression and Dysthymia

When the strictest criteria are used to sift through all the research literature on the pharmacological treatment of depression and dysthymia, only using large studies with low bias and meticulously designed trials, interestingly, only two studies since 2000 made the grade (with 90% certainty, using AI algorithm): In sum, using sertraline or imipramine does […]
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Association between dietary glycemic index and glycemic load with depression: a systematic review | SpringerLink Simple sugars and high GI foods make you depressed.

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial – The Lancet For us, this compares the UBC and MDA groups doing TMS in the Lower Mainland. Looks like both work equally well.

antidepressants for insomnia: the highest evidence thus far. basically trazodone and doxepin are reasonable alternatives to z drugs

Chief complaint: Homicidal. Assessing violence risk | MDedge Psychiatry your patient likely to become violent?

Keep saying yes to fish twice a week for heart health — ScienceDaily The advisory was written by a panel of nutrition experts, who also reviewed studies about mercury in fish. Mercury is found in most seafood but is prevalent in large fish such as shark, swordfish, tilefish, king mackerel, bigeye tuna, marlin and orange roughy. The writing group concluded that while mercury contamination may be associated […]
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Smarter brains run on sparsely connected neurons — ScienceDaily “Intelligent brains possess lean, yet efficient neuronal connections,” concludes Erhan Genç. “Thus, they boast high mental performance at low neuronal activity.”

Brain abnormality indicates general risk for mental illness: A new study identifies functional connectivity impairments associated with transdiagnostic risk for common forms of mental illness — ScienceDaily Authors conclude: “These patterns suggest that broad risk for mental illness may reflect subtle problems in how a person is able to integrate their thoughts, plans, and actions with their fundamental experience of the world, which in humans is principally represented by visual information,” said Mr. Elliott.