This study alerts us to the correlation between heart attacks and depression, confirms depression as a risk factor for cardiac disease and premature mortality. What this study does NOT clarify is whether the antidepressants themselves contribute to that risk. Further studies will need to be conducted to answer that question. Other studies have shown antidepressants to lower risk of heart attack, or contradictory reports on whether they help or are inert in preventing the next one. Remember: SSRIs tend to thin the blood by interfering with platelet function; this is supposed to reduce risk of atherosclerosis by preventing blood clot formation.