https://www.medscape.com/features/slideshow/anti-obesity-drugs

Weight loss programs are using medications now. BMI determines choice.
Also, newer targets aim for BMI of less than or equal to 22-23, and waists of 77 and 83, women and men. all
Tall order! Losing kgs, lowers your risk for heart attack, by about 13%/4-5mg lost, roughly.